GMO molecular characterization details

GMO detailed information

GMO:
DP305423 x DAS44406
Alias:
UID:
DP-3Ø5423-1 x DAS-444Ø6-6
Tradename:

Enlist E3, Plenish, Treus
Companies/Institutions:
MS Technologies, DOW AgroSciences, DuPont, Pioneer Hi-Bred International, Corteva Agriscience
Species:
Glycine max
(soybean)
Traits:
EU authorisation:

no Reference materials could be found

Detection Methods

20 results

Name	Type	Target	Description	Validation	Standardisation	Verification
QL-CON-CsVMV F/patsyn R	construct-specific	DAS44406, DAS68416, DAS81419	Qualitative real-time PCR (TaqMan) method for detection of the junction between the Cassava vein mosaic virus promoter (P-CsVMV) and the phosphinothricin N-acetyltransferase (pat) gene. Part of the qualitative triplex real-time PCR (TaqMan) method for detection of Ti plasmid (AgroBorder) sequences and a sequence of the Cassava vein mosaic virus promoter pat construct (P-CsVMV-pat) for screening for components of genetically modified organisms in food (Official Collection of Methods according to § 64 LFGB, L 00.00-176)	ring trial validation	national standard	1
QL-ELE-00-021	element-specific	CS-pat-STRVR	Qualitative real-time PCR (SYBRGreen) method for detection of CS-pat-STRVR (Barbau-Piednoir et al., 2014)	ring trial validation	unknown	1
QL-ELE-00-025	element-specific	CS-pat-STRVR	Qualitative real-time PCR (TaqMan) method for detection of the synthetic phosphinothricin acetyltransferase (pat) gene (BVL L00.00-154). EU-RL GMFF GMOMETHODS database as of December 23, 2016.	ring trial validation	EU reference method	1
QL-ELE-Patf-n2/Patr-n2	element-specific	CS-pat-STRVR	Qualitative real-time PCR (TaqMan) method for detection of the pat gene (Xu et al., 2006)	in-house validation	none	1
QL-ELE-T-g7-F/T-g7-R	element-specific	T-orf23-RHIRD, T-transcript 7	Qualitative real-time PCR (TaqMan) method for detection of the g7 terminator from Agrobacterium tumefaciens (Debode et al., 2013)	in-house validation	none	1
QL-TAX-GM-001	taxon-specific	Glycine max	Qualitative real-time PCR (SYBRGreen) method for detection of soybean lectin gene (Barbau-Piednoir et al., 2014)	ring trial validation	unknown	1
QL-TAX-GM-002	taxon-specific	Glycine max	Qualitative conventional PCR method for detection of soybean lectin gene (ISO/FDIS 21569).	ring trial validation	ISO standard	1
QL-TAX-GM-008	taxon-specific	Glycine max	Qualitative conventional PCR method for detection of soybean lectin gene (ISO 21569)	ring trial validation	ISO standard	1
QT-CON-00-008	construct-specific	DAS44406, FG72, GA21, GHB614, GHB811	Quantitative real-time PCR (TaqMan) method for detection of maize event GA21 (Shindo et al., 2002)	ring trial validation	ISO standard	1
QT-ELE-00-002	element-specific	CS-pat-STRVR	Quantitative real-time PCR (TaqMan) method for detection of phosphinothricin N-acetyltransferase gene (Weighardt et al., 2004) (EURL GMFF GMOMETHODS database as of February 5, 2020)	ring trial validation	unknown	1
QT-EVE-GM-008	event-specific	DP305423	Quantitative real-time PCR (TaqMan) method for detection of soybean event DP305423 (EU-RL GMFF GMOMETHODS database as of January 23, 2014)	ring trial validation	EU reference method	1
QT-EVE-GM-015	event-specific	DAS44406	Quantitative PCR method for detection of soybean event DAS44406 (EURL GMFF GMOMETHODS database as of May 28, 2015)	ring trial validation	EU reference method	1
QT-TAX-GM-001	taxon-specific	Glycine max	Quantitative real-time PCR (TaqMan) method for detection of soybean lectin gene	ring trial validation	ISO standard	1
QT-TAX-GM-002	taxon-specific	Glycine max	Quantitative real-time PCR (TaqMan) method for detection of soybean lectin gene (ISO 21570). Estimated number of target copies per haploid genome (Jacchia et al. 2018): 1	ring trial validation	ISO standard	1
QT-TAX-GM-003	taxon-specific	Glycine max	Quantitative real-time PCR (TaqMan) method for detection of soybean lectin (Le1) gene (EU-RL GMFF GMOMETHODS database as of July 2020). Estimated number of target copies per haploid genome (Jacchia et al. 2018): 1	ring trial validation	EU reference method	1
QT-TAX-GM-004	taxon-specific	Glycine max	Quantitative real-time PCR (TaqMan) method for detection of soybean lectin gene (Hird et al., 2003).	ring trial validation	unknown	1
QT-TAX-GM-005	taxon-specific	Glycine max	Quantitative real-time PCR (TaqMan) for detection of soybean lectin gene (EU-RL GMFF GMOMETHODS database as of November 8, 2023).	ring trial validation	EU reference method	1
QT-TAX-GM-007	taxon-specific	Glycine max	Quantitative real-time PCR (TaqMan) method for detection of soybean lectin gene	ring trial validation	ISO standard	1
QT-TAX-GM-009	taxon-specific	Glycine max	Quantitative real-time PCR (TaqMan) method for detection of soybean lectin (Le1) gene (EU-RL GMFF GMOMETHODS database as of January 22, 2014)	ring trial validation	EU reference method	1
QT-TAX-GM-020	taxon-specific	Glycine max	Quantitative real-time PCR (TaqMan) method for detection of soybean lectin (Le1) gene (EU-RL GMFF GMOMETHODS database as of January 22, 2014). Estimated number of target copies per haploid genome (Jacchia et al. 2018): 1	ring trial validation	EU reference method	1

Description:	For Reference Materials, please consult the materials mentioned under the single GMO events.
Links regarding to this GMO:
Transformation / Modification technique:	conventional crossing

Citation	Publication year	Publishing authority	Publication type	Content types
Application for authorisation of genetically modified plants and derived food and feed in accordance with Regulation (EC) No 1829/2003. 305423 x DAS-44406-6 soybean, GMFF-2024-29150 AP195, Part VII – Summary of Application	2024	EFSA	application summary	application summary
Application for renewal of authorisation of genetically modified DP305423 soybean and derived food and feed in accordance with articles 11 and 23 of Regulation (EC) No 1829/2003, GMFF-2024-23560 RX046, Summary of Application	2024	EFSA	application summary	application summary
COMMISSION IMPLEMENTING DECISION (EU) 2017/2448 of 21 December 2017 authorising the placing on the market of products containing, consisting of, or produced from genetically modified soybean 305423 × 40-3-2 (DP-3Ø5423-1 × MON-Ø4Ø32-6) pursuant to Regulation (EC) No 1829/2003 of the European Parliament and of the Council on genetically modified food and feed (notified under document C(2017) 9040)	2017	EU	EU Commission Decision	decision document
Overall opinion of the European Food Safety Authority on application (EFSA-GMO-NL-2012-106) by Dow AgroSciences LLC for placing on the market of genetically modified herbicide-tolerant soybean DAS-44406-6 for food and feed uses, import and processing in accordance with Articles 6 and 18 of Regulation (EC) No 1829/2003	2017	EFSA	EFSA overall opinion	risk assessment document
COMMISSION IMPLEMENTING DECISION (EU) 2017/2450 of 21 December 2017 authorising the placing on the market of products containing, consisting of, or produced from genetically modified soybean DAS-44406-6, pursuant to Regulation (EC) No 1829/2003 of the European Parliament and of the Council on genetically modified food and feed (notified under document C(2017) 9042)	2017	EU	EU Commission Decision	decision document
Scientific opinion on an application by Dow AgroSciences LLC (EFSA-GMO-NL-2012-106) for the placing on the market of genetically modified herbicide-tolerant soybean DAS-44406-6 for food and feed uses, import and processing under Regulation (EC) No 1829/2003	2017	EFSA GMO Panel	Scientific opinion EFSA GMO Panel	risk assessment document
COMMISSION IMPLEMENTING DECISION (EU) 2015/698 of 24 April 2015 authorising the placing on the market of products containing, consisting of, or produced from genetically modified soybean 305423 (DP-3Ø5423-1) pursuant to Regulation (EC) No 1829/2003 of the European Parliament and of the Council (notified under document C(2015) 2773)	2015	EU	EU Commission Decision	decision document
TECHNICAL REPORT Overall opinion of the European Food Safety Authority in accordance with Articles 6 and 18 of Regulation (EC) No 1829/2003 on application (reference EFSA-GMO-NL-2007-45) for the placing on the market of herbicide tolerant, high oleic acid genetically modified soybean 305423 for food and feed uses, import and processing under Regulation (EC) No 1829/2003 from Pioneer	2013	EFSA	EFSA overall opinion	risk assessment document
SCIENTIFIC OPINION Scientific Opinion on application EFSA-GMO-NL-2007-45 for the placing on the market of herbicide-tolerant, high-oleic acid, genetically modified soybean 305423 for food and feed uses, import and processing under Regulation (EC) No 1829/2003 from Pioneer	2013	EFSA GMO Panel	Scientific opinion EFSA GMO Panel	risk assessment document
Application for authorisation of DAS-444Ø6-6 soybean grain for all uses as for any other soybean, excluding cultivation, according to Articles 5 and 17 of Regulation (EC) No 1829/2003 on genetically modified food and feed - Part VII - Summary	2013	EFSA	application summary	application summary
Mathesius, C. A., Barnett, J. F., Jr., Cressman, R. F., Ding, J., Carpenter, C., Ladics, G. S., . . . Delaney, B. (2009). Safety assessment of a modified acetolactate synthase protein (GM-HRA) used as a selectable marker in genetically modified soybeans. Regulatory Toxicology and Pharmacology, 55(3), 309-320.	2009	Research group	peer-reviewed article	safety
Herouet-Guicheney, C., Rouquie, D., Freyssinet, M., Currier, T., Martone, A., Zhou, J., . . . Rouan, D. (2009). Safety evaluation of the double mutant 5-enol pyruvylshikimate-3-phosphate synthase (2mEPSPS) from maize that confers tolerance to glyphosate herbicide in transgenic plants. Regulatory Toxicology and Pharmacology, 54(2), 143-153.	2009	Research group	peer-reviewed article	safety
PART II SUMMARY SUMMARY OF THE APPLICATION FOR AUTHORISATION OF GENETICALLY MODIFIED 305423 SOYBEAN AND DERIVED FOOD AND FEED IN ACCORDANCE WITH REGULATION (EC) 1829/2003	2008	EFSA	application summary	application summary

European GMO Initiative for a Unified Database System

GMO detailed information

GMO:

Alias:

UID:

Tradename:

Companies/Institutions:

Species:

Traits:

EU authorisation:

General Information

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Inserts / Modification

Transformation Vectors

Detection Methods

Reference Materials

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Literature reference